The New Paradigm in Drug Discovery: Novel Drug Delivery System
Mantun Prasad Gupta, Ranjan Kumar Singh, Rajeswari Tanniru, Chennu MM Prasada Rao, Ajay Garg
Abstract:
Transforming a conventional medicinal molecule into a novel delivery method will help to increase patient efficacy, safety, and adherence. One could improve the effectiveness of a current medication molecule by utilizing a novel drug delivery method. Targeting drugs at specific areas and rates presents difficulties that a well-organized, novel drug delivery system successfully addresses. Pharmaceutical companies have been driven to create innovative drug delivery methods by the need for efficient drug administration with the lowest adverse effects. Important elements of novel drug delivery systems and their several categories are investigated in this paper. Initially started many years ago, the evolution of Novel Drug Delivery Systems (NDDS) has been rather advanced recently. Compared to conventional dose forms, NDDS offers advantages, including improved therapeutic results. In the new patent system, NDDS is chosen to bring fresh ideas into the controlled market. Microparticles, nanoparticles, osmotically modulated systems, transdermal therapeutic systems, aquasomes, dendrimers, multiple emulsions, micro-emulsions, liposomes, niosomes, pharmacophores, self-regulating systems, and brain-targeted delivery systems have been developed in recent years in many forms. India is showing a similar trend since certain pharmaceutical companies are shifting their attention towards NDDS development. Public and commercial sectors of research are being carried out in India, which is producing a range of items available on the market. In this study, we have summarized all the types of NDDS, their advantages, disadvantages, and prospects of NDDS which can be beneficial for new researchers in the treatment of some chronic diseases.
Keywords: Drug Delivery System, Novel Drug Delivery System, Nanoparticles, Transdermal Therapeutic Systems, Nanoparticles, Brain-Targeted Delivery Systems.
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