Abstract: 
Fast dissolving sublingual films is an emerging technology with rapid onset of action and improved patient compliance. It improves the efficacy of API’s and provides better drug utilisation. These formulations are suitable for cold, allergic rhinitis, asthma attacks, CNS disorders etc. where rapid onset of action is required for faster relief. The sublingual route of drug administration is very effective since, the drug absorbed through the sublingual blood vessels by passes hepatic first pass metabolic process and gives a better bioavailability. The present article overviews the materials used, formulation aspects, manufacturing methods, evaluation parameters and applications of fast dissolving films by sublingual route. Many patients find it difficult to swallow tablets and hard gelatin capsules particularly pediatric and geriatric patients and do not take their medicines as prescribed. Difficulty in swallowing or dysphasia is seen to afflict nearly 35% of the general population. In some cases such as motion sickness, sudden episode of allergic attack or coughing and an unavailability of water, the swallowing of tablet or capsules may become difficult, in such situation fast dissolving drug delivery system is alternative mode administering the drug.

Keywords: Sublingual Film, Fast Dissolving Film, Solvent Casting Method, Water Soluble Polymers, Ex Vivo Permeation Studies.