Formulation and Evaluation of Polyherbal Medicated Jelly
Sushmitha K, Sai Sirini P, Tejaswini C H, Bhuvaneshwari C H, Ashish Kumar S, Anil Kumar B
Abstract:
Medicated jellies are semi-solid dosage forms designed to deliver drug through the oral route with improved patient compliance, especially for pediatric and geriatric patients. The demand for natural immunity-boosting formulations has increased significantly due to growing health awareness. In this study, we selected medicinal plants such as Carica papaya, Piper betel, Withania somnifera and Morinda citrifolia. The medicated jellies were formulated using decoctions of Carica papaya (papaya) leaves and Piper betel (betel) leaves both known for immunomodulatory and antioxidant properties. The natural sweetening agents are used such as sugarcane molasses, stevia & jaggery. The jellies were prepared by heating and congealing method using natural gelling agents such as agar, gelatin, pectin. The prepared formulations were evaluated for physicochemical parameters including appearance, colour, odour, texture, pH, viscosity, syneresis, spreadability, invitro drug release. The physicochemical evaluation of the developed formulation has shown reddish brown colour, sweet pungent aroma, good spreadability, viscosity, syneresis, and pH almost near to saliva. The maximum amounts of % drug release of the formulations shown are F5-95.64%, F2-92.84%, F6-91.75%. So, the formulated jellies possess excellent potential as natural immunity boosters, their palatable taste, ease of administration. Further support is required to extend Future clinical and toxicological validation for market applications.
Keywords: Immunity, Polyherbal Medicated Jelly, Immunity Booster, Carica papaya, Piper betel.
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