Phytochemical Characterization and Hepatoprotective Potential of Plumbago Indica Root Extract in Experimental Models
Mane K R, Patil R N, Pandey A N
Abstract:
The present study aims to analyze and compare the secondary metabolites of Plumbago indica, a medicinal plant, using both qualitative and quantitative approaches. Qualitative analysis will be performed through various chemical tests and chromatography techniques, including thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC). Quantitative estimation of total phenolic and flavonoid contents will be carried out using UV–Vis spectroscopy. Plant material will be collected, and extracts will be prepared using different solvents for subsequent analysis of secondary metabolites. Identified metabolites will be evaluated for their therapeutic potential and compared with the traditional uses of Plumbago indica. The hepatoprotective effect of the ethanolic extract will be assessed using in vivo models. The study is expected to provide valuable insights into the hepatoprotective potential of Plumbago indica ethanolic extract. The findings suggest that the extract can protect the liver from damage caused by free radicals generated during CCl₄ metabolism, highlighting its potential as a therapeutic agent for liver disorders.
Keywords: Plumbago Indica, Qualitative, Quantitative Phytochemical, Antioxidant Activity, Hepatoprotective.
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