Volume 3

January-March 2011

Polymeric intercalated silicate nanocomposites: An approach to controlled drug delivery

Debajyoti Ray

Abstract:
Nanocomposite of 2-Ethyl hexylacrylate (EHA) and acrylic acid (AA) intercalated with sodium silicate (SS) was prepared by emulsion technique using benzoyl peroxide (BPO) as reaction initiator. The transmittance electron microscopy showed the well dispersion of the polymer nanocomposite into the intercalated silicate layers. The novel nanocomposite was further characterized by NMR, IR, TGA and exhibited excellent properties of higher thermal stability and super absorbency for use as high performance materials. P(EHA-co-AA)/silicate nanocomposite was found to have better swelling capacity in simulated intestinal fluid. So the nanosystem is expected to be useful as controlled drug delivery device in future.

Keywords: Intercalation, Nanocomposite, Swelling Studies, Degradation Studies.