Abstract:
The preparation methods for nanosuspension formulation include both top-down methods like wet milling, dry milling, high-pressure homogenization, and co-grinding, and bottom-up methods. These methods help in enhancing the solubility of poorly water-soluble drugs, providing a promising alternative to traditional formulations. Additionally, the evaluation of nanosuspensions involves assessing various formulation parameters to determine factors such as enhanced dissolution and bioavailability. By considering components, preparation methods, process parameters, and administration routes, researchers aim to optimize nanosuspension formulations for different applications. These strategies help in developing effective nanosuspensions for various administration routes.

Keywords: Nanosuspensions, Top-down Methods, Bioavailability, Evaluation Parameters.