Abstract: 
Pharmaceutical research is achieving and focusing new goals within the field of delivery systems, that square measure helpful to aggravate therapeutic objectives while alleviating side effects. Multiparticulates are discrete particles that make a multiple unit system. Pelletization is the technique to convert drugs or excipients into small free flowing, spherical or semi spherical units, which are produced by agglomerating fine powdered drug or excipients with a binder solution. Pellets range in a size, typically between 0.5-2.0mm. Multiple Unit Particulate System (MUPS) are multi-particulate in nature and are administered as tablets. These tablets gets disperse in the stomach and intestine, allowing constant drug release in systemic circulation. In comparison with single traditional dosage form, in the Micro particulate system dosage form of the drug has been divided among various discrete delivery entities. This article reviews the classification, advantages, disadvantages, common industrial technique for preparation of pellets.

Keywords: Micro Particulates, MUPS, Pelletization, Spheronization.