Design, Development and Evaluation of Anthelmintic Candy for Paediatric Use
Sanjana S, Sneha H C
Abstract:
There was a need for innovative dosage forms that would both minimize first pass metabolism and boost bioavailability despite the wide variety of dosage forms already on the market. The goal of the enhanced research effort was to decrease first pass metabolism and increase bioavailability. Due to its simplicity of swallowing, ability to prevent pain, and most importantly patient compliance, the oral route of medication administration was a very popular form of drug administration. Candy was designed to dissolve gradually in the tongue and was a solid dose form that contained medication in a foundation that was sweetened and flavoured. Candies are pharmaceutical dose forms that are meant to be given to children. They contain albendazole in order for the candy to melt readily in the child’s mouth. After boiling sugar and water to make candy, the medication albendazole was added and thoroughly blended. The prepared liquid was poured into the calibrated mold, and it was left outside to dry for a few hours. The made candy was stored in desiccators, wrapped in aluminium foil to keep moisture out.
Keywords: Albendazole, Medicated candy, Anthilmintic.
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