Abstract:
Herbal medicines is still the mainstay of about 75-80% of the world’s population, mainly in developing countries, for primary health care because of better compatibility with human body, cultural acceptability and lesser side effects. Plants for thousands of years have been used to enhance health and for medicinal purposes. Psidium guajava and Punica granatum, are one which has an enormous wealth of medicinal value. It for long has been known for its anti-inflammatory, antimicrobial, antioxidant, antidiarrheal, antimutagenic properties. Despite of its widespread biologic uses there is a dearth of information on its therapeutic effect in the treatment of periodontal diseases. The objectives of present investigation were to formulate and evaluate herbal gel for periodontic treatment. Six formulations were made, two are of aqueous extract, two are of methanolic extract, two are of finely dried leaf, Carbopol 934 is used as a gel base. Formulations were evaluated for various parameters like physical appearance, pH, homogeneity, spreadability, viscosity, extrudability. The formulated gels were transparent, homogeneous and pH ranges from 7 to 7.5. Formulation showed acceptable rheological behaviour with applicable spreadability and extrudability properties. Present herbal formulation was developed with very safe with good stability and effective over to synthetic formulations for the treatment of periodontics. This research work gives the information reported in this contributes scientifically to recognizing the importance of the pomegranate and guava as a target in the search for new biotechnological investments and herbal formulation.

Keywords: Periodontics, Herbal Formulation, Carbopol 934, Pomegranate, Guava, Herbal Gel.