Volume 13

January-March 2021​

Formulation and quality evaluation of films prepared from ethanolic extract of ‎‎Carica ‎papaya‎‎ – gelatin composite for wound healing treatment: In-vitro‎‎ studies

M Abd Elgadir

Abstract:
The objective of this research paper was to evaluate wound healing films prepared from a composition of gelatin- Carica papaya extract using methods for wound healing purposes. Five films (F1-F5) were prepared from Carica papaya extract (100–500 mg) and gelatin (1000 mg). The casting technique was used to formulate the films. The films were evaluated for pH value, thickness, water absorption capacity, folding endurance, tensile strength and extract release properties. Increasing the extract of Carica papaya in the formulated film caused significant increases (p ≤ 0.05) in most evaluated parameters (Film thickness, water absorption capacity, folding endurance, tensile strength and extract release). However, increasing the extract of Carica papaya caused significant decreases (p ≤ 0.05) in the pH values of the films. Therefore, these results revealed that Carica papaya /Gelatin films could be a promising pharmaceutical candidate for wound healing treatment.

Keywords: Carica Papaya, Wound Healing, Ethanolic Extract, Extract Release.