Volume 8

July-September 2016

Nanoemulsions: A versatile mode of drug delivery system

Hitendra S Mahajan, Sagar K Savale

Abstract: 
A versatile mode of drug delivery system has been developed to overcome the drawbacks associated in conventional drug delivery system. This review was giving detailed idea about Nanoemulsion system. Nanoemulsion is promising delivery of various drugs. It is nanosized submicron sized emulsions, which are manufactured for improving the delivery of active pharmaceutical ingredients. Nanoemulsion was thermodynamically as well as kinetically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of an emulsifying agent (Smix). The droplet size was falls typically in the range of 50-200 nm. The main difference between emulsion, microemulsion and nanoemulsion lies in the size and shape of particles dispersed in the continuous Phase. Nanoemulsion offers a promising vehicle for increasing the aqueous solubility of poorly water soluble drugs and enhances the Pharmacological as well as Therapeutic action of drugs. The design and development of nanoemulsions aimed at controlling or improving required bioavailability levels of Pharmaceutical agents. In this review, the attention is focused to give a basic idea about its Introduction, advantages, disadvantages, components, factors, mechanism, formulation method, evaluation and applications of Nanoemulsion system. It also focused in Nanoemulsion system Comparision between emulsion and microemulsion system.

Keywords: Nanoemulsion, Microemulsion, Submicron Sized Emulsions, Drug Delivery, Emulgents, Novel Drug Delivery, Versatile Drug Delivery.