Volume 8

July-September 2016

Niosome: A vesicular weapon for targeted and controlled drug delivery

Vivek P Chavda

Abstract: 
An appropriate drug concentration at the site of action for sufficient period of time is desired for cogent pharmacotherapeutics. Vesicular drug delivery system is a mean to achieve this goal with enhanced bioavailability. Niosome is such vesicular mean containing nonionic surfactants and cholesterol. Longer shelf life, stability and ability to deliver drug at target site in a controlled or sustained manner are some of its unique credentials. The present review has been grafted to highlight some of the fascinating features of niosome as drug delivery vehicle. It includes formulation aspect of niosome, its types, preparation methods, stability, toxicity, its characterization and lastly glimpses of its pharmaceutical utilities are being enumerated.

Keywords: Niosome, Nonionic Surfactant, Cholesterol, Aspasomes, Stability.