Abstract:
The Limonia acidissima L is one of the useful traditional medicinal plants. In the rural area a lot of people use the Limonia acidissima L. for treating indigestion, flatulence, diarrhoea, dysentery and haemorrhoids. The present study was aimed to evaluate the various pharmacological efficacies of methanolic and acetonic fruit peels extracts of Limonia acidissima L. For cytotoxic activity, methanolic and acetonic extracts showed LC₅₀ value 76.73 and 68.31μg/ml; respectively. On the other hand, the reference standard vincristine sulphate showed LC₅₀ value was 2.63 μg/ml. In the thrombolytic activity the methanolic and acetonic extracts showed clot lysis (32.89%) and (32.43%); respectively. The standard of Streptokinase showed clot lysis (68.42%). This study will reveal the phytochemicals, cytotoxic and thrombolytic activity which may be used in future to open a new line of investigation.

Keywords: Fruit Peels, Streptokinase, % of Clot Lysis, Cytotoxic Activity, Vincristine Sulphate.