Volume 10

January-March 2018

Development and evaluation of ‎banana pulp powder as a ‎pharmaceutical excipient

Ravindra R Patil, ‎Yuvraj S Pawara, ‎Nayana Mahajan, ‎Hitendra S Mahajan

Abstract:
The study was aimed extraction of banana powder from banana pulp; The presence of carbohydrate was confirmed by phytochemical analysis. The drugs and extract were found to be compatible as confirmed by IR spectral studies. The banana powder was evaluated for its micromeritic properties viz. suspending properties, Sedimentation volume, redispersibility, pH measurement, viscosity measurement and particle size. The formulations were prepared using Musa Paradisiacal pulp powder and other excipient. Suspension prepared by using Musa Paradisiacal pulp powder were found to be easily redispersible than other suspensions. Studies indicate that the pulp of Musa paradisiacal may be used as a pharmaceutical adjuvant and as a suspending agent at 2-4%w/v, concentration. This study confirmed that the banana pulp can be used as an effective release retardant and can be successfully used in commercial products. Ofloxacin suspension was prepared by using musa paradisiacal pulp powder as suspending agent and the suspension was evaluated for its various parameters and dissolution studies.

Keywords: Novel Excipient, Antimicrobial Drug, Suspending Agents, Suspension.